TAp73 enhances the pentose phosphate pathway and supports cell proliferation

TAp73 is a structural homologue of the pre-eminent tumor suppressor p53. However, unlike p53, TAp73 is rarely mutated, and instead is frequently over-expressed in human tumors. It remains unclear whether TAp73 affords an advantage to tumor cells and if so, what is the underlying mechanism. Here we s...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Wenjing, Jiang, Peng, Mancuso, Anthony, Stonestrom, Aaron, Brewer, Michael D., Minn, Andy J., Mak, Tak W., Wu, Mian, Yang, Xiaolu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733810/
https://www.ncbi.nlm.nih.gov/pubmed/23811687
http://dx.doi.org/10.1038/ncb2789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733810/
https://www.ncbi.nlm.nih.gov/pubmed/23811687
http://dx.doi.org/10.1038/ncb2789

Ejemplares similares