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Structures of an Apo and a Binary Complex of an Evolved Archeal B Family DNA Polymerase Capable of Synthesising Highly Cy-Dye Labelled DNA

Thermophilic DNA polymerases of the polB family are of great importance in biotechnological applications including high-fidelity PCR. Of particular interest is the relative promiscuity of engineered versions of the exo- form of polymerases from the Thermo- and Pyrococcales families towards non-canon...

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Detalles Bibliográficos
Autores principales: Wynne, Samantha A., Pinheiro, Vitor B., Holliger, Philipp, Leslie, Andrew G. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733885/
https://www.ncbi.nlm.nih.gov/pubmed/23940661
http://dx.doi.org/10.1371/journal.pone.0070892