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(3)H-Deprenyl and (3)H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain

BACKGROUND: The pathological features in Alzheimer’s disease (AD) brain include the accumulation and deposition of β-amyloid (Aβ), activation of astrocytes and microglia and disruption of cholinergic neurotransmission. Since the topographical characteristics of these different pathological processes...

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Detalles Bibliográficos
Autores principales: Marutle, Amelia, Gillberg, Per-Göran, Bergfors, Assar, Yu, Wenfeng, Ni, Ruiqing, Nennesmo, Inger, Voytenko, Larysa, Nordberg, Agneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733895/
https://www.ncbi.nlm.nih.gov/pubmed/23880036
http://dx.doi.org/10.1186/1742-2094-10-90