LDLR(–/–)ApoB(100/100) mice with insulin-like growth factor II overexpression reveal a novel form of retinopathy with photoreceptor atrophy and altered morphology of the retina

PURPOSE: The aim of this study was to characterize the ocular morphology of low-density lipoprotein receptor–deficient apolipoprotein B-100-only mice, where overexpression of insulin-like growth factor II (IGF-II) has been shown to induce glucose intolerance and increase atherosclerotic lesion progr...

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Detalles Bibliográficos
Autores principales: Kinnunen, Kati, Heinonen, Suvi E., Kalesnykas, Giedrius, Laidinen, Svetlana, Uusitalo-Järvinen, Hannele, Uusitalo, Hannu, Ylä-Herttuala, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733910/
https://www.ncbi.nlm.nih.gov/pubmed/23922490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733910/
https://www.ncbi.nlm.nih.gov/pubmed/23922490

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