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LDLR(–/–)ApoB(100/100) mice with insulin-like growth factor II overexpression reveal a novel form of retinopathy with photoreceptor atrophy and altered morphology of the retina
PURPOSE: The aim of this study was to characterize the ocular morphology of low-density lipoprotein receptor–deficient apolipoprotein B-100-only mice, where overexpression of insulin-like growth factor II (IGF-II) has been shown to induce glucose intolerance and increase atherosclerotic lesion progr...
Autores principales: | Kinnunen, Kati, Heinonen, Suvi E., Kalesnykas, Giedrius, Laidinen, Svetlana, Uusitalo-Järvinen, Hannele, Uusitalo, Hannu, Ylä-Herttuala, Seppo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733910/ https://www.ncbi.nlm.nih.gov/pubmed/23922490 |
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