Akt-Induced Phosphorylation of N-CoR at Serine 1450 Contributes to Its Misfolded Conformational Dependent Loss (MCDL) in Acute Myeloid Leukemia of the M5 Subtype

The nuclear receptor co-repressor (N-CoR) is a key component of the generic co-repressor complex that plays an important role in the control of cellular growth and differentiation. As shown by us recently, the growth suppressive function of N-CoR largely relies on its capacity to repress Flt3, a key...

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Detalles Bibliográficos
Autores principales: Nin, Dawn Sijin, Ali, Azhar Bin, Okumura, Koichi, Asou, Norio, Chen, Chien-Shing, Chng, Wee Joo, Khan, Matiullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733915/
https://www.ncbi.nlm.nih.gov/pubmed/23940660
http://dx.doi.org/10.1371/journal.pone.0070891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733915/
https://www.ncbi.nlm.nih.gov/pubmed/23940660
http://dx.doi.org/10.1371/journal.pone.0070891

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