Insights into the N-Sulfation Mechanism: Molecular Dynamics Simulations of the N-Sulfotransferase Domain of Ndst1 and Mutants

Sulfation patterns along glycosaminoglycan (GAG) chains dictate their functional role. The N-deacetylase N-sulfotransferase family (NDST) catalyzes the initial downstream modification of heparan sulfate and heparin chains by removing acetyl groups from subsets of N-acetylglucosamine units and, subse...

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Detalles Bibliográficos
Autores principales: Gesteira, Tarsis F., Pol-Fachin, Laércio, Coulson-Thomas, Vivien Jane, Lima, Marcelo A., Verli, Hugo, Nader, Helena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733922/
https://www.ncbi.nlm.nih.gov/pubmed/23940657
http://dx.doi.org/10.1371/journal.pone.0070880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733922/
https://www.ncbi.nlm.nih.gov/pubmed/23940657
http://dx.doi.org/10.1371/journal.pone.0070880

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