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Proteomic Analysis of Signaling Network Regulation in Renal Cell Carcinomas with Differential Hypoxia-Inducible Factor-2α Expression

BACKGROUND: The loss of von Hippel–Lindau (VHL) protein function leads to highly vascular renal tumors characterized by an aggressive course of disease and refractoriness to chemotherapy and radiotherapy. Loss of VHL in renal tumors also differs from tumors of other organs in that the oncogenic casc...

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Detalles Bibliográficos
Autores principales: Nagaprashantha, Lokesh Dalasanur, Talamantes, Tatjana, Singhal, Jyotsana, Guo, Jia, Vatsyayan, Rit, Rauniyar, Navin, Awasthi, Sanjay, Singhal, Sharad S., Prokai, Laszlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733962/
https://www.ncbi.nlm.nih.gov/pubmed/23940778
http://dx.doi.org/10.1371/journal.pone.0071654