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Properties of Local Interactions and Their Potential Value in Complementing Genome-Wide Association Studies

Local interactions between neighbouring SNPs are hypothesized to be able to capture variants missing from genome-wide association studies (GWAS) via haplotype effects but have not been thoroughly explored. We have used a new high-throughput analysis tool to probe this underexplored area through full...

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Detalles Bibliográficos
Autores principales: Wei, Wenhua, Gyenesei, Attila, Semple, Colin A. M., Haley, Chris S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733963/
https://www.ncbi.nlm.nih.gov/pubmed/23940718
http://dx.doi.org/10.1371/journal.pone.0071203