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Amelioration of Murine Passive Immune Thrombocytopenia by IVIg and a Therapeutic Monoclonal CD44 Antibody Does Not Require the Myd88 Signaling Pathway

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by a low platelet count and the production of anti-platelet antibodies. The majority of ITP patients have antibodies to platelet integrin α(IIb)β(3) (GPIIbIIIa) which can direct platelet phagocytosis by macrophages. One e...

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Detalles Bibliográficos
Autores principales: Crow, Andrew R., Yu, Honghui, Han, Dongji, Lazarus, Alan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733967/
https://www.ncbi.nlm.nih.gov/pubmed/23940791
http://dx.doi.org/10.1371/journal.pone.0071882