Tylophorine, a phenanthraindolizidine alkaloid isolated from Tylophora indica exerts antiangiogenic and antitumor activity by targeting vascular endothelial growth factor receptor 2–mediated angiogenesis

BACKGROUND: Anti-angiogenesis targeting VEGFR2 has been considered as an important strategy for cancer therapy. Tylophorine is known to possess anti-inflammatory and antitumor activity, but its roles in tumor angiogenesis, the key step involved in tumor growth and metastasis, and the involved molecu...

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Detalles Bibliográficos
Autores principales: Saraswati, Sarita, Kanaujia, Pawan K, Kumar, Shakti, Kumar, Ranjeet, Alhaider, Abdulqader A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733984/
https://www.ncbi.nlm.nih.gov/pubmed/23895055
http://dx.doi.org/10.1186/1476-4598-12-82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733984/
https://www.ncbi.nlm.nih.gov/pubmed/23895055
http://dx.doi.org/10.1186/1476-4598-12-82

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