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Interleukin-5 Supports the Expansion of Fas Ligand-Expressing Killer B Cells that Induce Antigen-Specific Apoptosis of CD4(+) T Cells and Secrete Interleukin-10

Beyond their critical role in humoral immunity, B lymphocytes can employ a variety of immunomodulatory mechanisms including expression of the apoptosis-inducing molecule Fas ligand (FasL; CD178). Here, we extensively characterized the surface phenotype of FasL(+) killer B cells, showing they are enr...

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Detalles Bibliográficos
Autores principales: Klinker, Matthew W., Reed, Tamra J., Fox, David A., Lundy, Steven K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734024/
https://www.ncbi.nlm.nih.gov/pubmed/23940537
http://dx.doi.org/10.1371/journal.pone.0070131