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HIV-1 Nef promotes the localization of Gag to the cell membrane and facilitates viral cell-to-cell transfer

BACKGROUND: Newly synthesized HIV-1 particles assemble at the plasma membrane of infected cells, before being released as free virions or being transferred through direct cell-to-cell contacts to neighboring cells. Localization of HIV-1 Gag precursor at the cell membrane is necessary and sufficient...

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Detalles Bibliográficos
Autores principales: Malbec, Marine, Sourisseau, Marion, Guivel-Benhassine, Florence, Porrot, Françoise, Blanchet, Fabien, Schwartz, Olivier, Casartelli, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734038/
https://www.ncbi.nlm.nih.gov/pubmed/23899341
http://dx.doi.org/10.1186/1742-4690-10-80