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Association between Genetic Polymorphisms in Ca(v)2.3 (R-type) Ca(2+) Channels and Fentanyl Sensitivity in Patients Undergoing Painful Cosmetic Surgery

Individual differences in the sensitivity to fentanyl, a widely used opioid analgesic, lead to different proper doses of fentanyl, which can hamper effective pain treatment. Voltage-activated Ca(2+) channels (VACCs) play a crucial role in the nervous system by controlling membrane excitability and c...

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Detalles Bibliográficos
Autores principales: Ide, Soichiro, Nishizawa, Daisuke, Fukuda, Ken-ichi, Kasai, Shinya, Hasegawa, Junko, Hayashida, Masakazu, Minami, Masabumi, Ikeda, Kazutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734060/
https://www.ncbi.nlm.nih.gov/pubmed/23940630
http://dx.doi.org/10.1371/journal.pone.0070694