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Association between Genetic Polymorphisms in Ca(v)2.3 (R-type) Ca(2+) Channels and Fentanyl Sensitivity in Patients Undergoing Painful Cosmetic Surgery
Individual differences in the sensitivity to fentanyl, a widely used opioid analgesic, lead to different proper doses of fentanyl, which can hamper effective pain treatment. Voltage-activated Ca(2+) channels (VACCs) play a crucial role in the nervous system by controlling membrane excitability and c...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734060/ https://www.ncbi.nlm.nih.gov/pubmed/23940630 http://dx.doi.org/10.1371/journal.pone.0070694 |