Polymorphism of ORM1 Is Associated with the Pharmacokinetics of Telmisartan

BACKGROUND: The pharmacokinetics (PKs) and pharmacodynamics (PDs) of telmisartan varies among the individuals, and the main causes remain unknown. The aim of this study was to evaluate the impact of ORM1, as well as ABCC2, ABCB1, ABCG2 and SLCO1B3 polymorphisms, on the disposition of the drug and BP...

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Detalles Bibliográficos
Autores principales: Chen, Wang-Qing, Shu, Yan, Li, Qing, Xu, Lin-Yong, Roederer, Mary W., Fan, Lan, Wu, Lan-Xiang, He, Fa-Zhong, Luo, Jian-Quan, Tan, Zhi-Rong, He, Yi-Jing, Zhou, Hong-Hao, Chen, Xiang, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734062/
https://www.ncbi.nlm.nih.gov/pubmed/23940561
http://dx.doi.org/10.1371/journal.pone.0070341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734062/
https://www.ncbi.nlm.nih.gov/pubmed/23940561
http://dx.doi.org/10.1371/journal.pone.0070341

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