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Possible Role of the Glycogen Synthase Kinase-3 Signaling Pathway in Trimethyltin-Induced Hippocampal Neurodegeneration in Mice

Trimethyltin (TMT) is an organotin compound with potent neurotoxic effects characterized by neuronal destruction in selective regions, including the hippocampus. Glycogen synthase kinase-3 (GSK-3) regulates many cellular processes, and is implicated in several neurodegenerative disorders. In this st...

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Detalles Bibliográficos
Autores principales: Kim, Juhwan, Yang, Miyoung, Kim, Sung-Ho, Kim, Jong-Choon, Wang, Hongbing, Shin, Taekyun, Moon, Changjong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734066/
https://www.ncbi.nlm.nih.gov/pubmed/23940567
http://dx.doi.org/10.1371/journal.pone.0070356