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DNA structure-specific priming of ATR activation by DNA-PKcs

Three phosphatidylinositol-3-kinase–related protein kinases implement cellular responses to DNA damage. DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and ataxia-telangiectasia mutated respond primarily to DNA double-strand breaks (DSBs). Ataxia-telangiectasia and RAD3-related (ATR) signa...

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Detalles Bibliográficos
Autores principales: Vidal-Eychenié, Sophie, Décaillet, Chantal, Basbous, Jihane, Constantinou, Angelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734074/
https://www.ncbi.nlm.nih.gov/pubmed/23897887
http://dx.doi.org/10.1083/jcb.201304139