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Mutually dependent degradation of Ama1p and Cdc20p terminates APC/C ubiquitin ligase activity at the completion of meiotic development in yeast

BACKGROUND: The execution of meiotic nuclear divisions in S. cerevisiae is regulated by protein degradation mediated by the anaphase promoting complex/cyclosome (APC/C) ubiquitin ligase. The correct timing of APC/C activity is essential for normal chromosome segregation. During meiosis, the APC/C is...

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Detalles Bibliográficos
Autores principales: Tan, Grace S, Lewandowski, Rebecca, Mallory, Michael J, Strich, Randy, Cooper, Katrina F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734102/
https://www.ncbi.nlm.nih.gov/pubmed/23816140
http://dx.doi.org/10.1186/1747-1028-8-9