An integrated hierarchical Bayesian approach to normalizing left-censored microRNA microarray data

BACKGROUND: MicroRNAs (miRNAs) are small endogenous ssRNAs that regulate target gene expression post-transcriptionally through the RNAi pathway. A critical pre-processing procedure for detecting differentially expressed miRNAs is normalization, aiming at removing the between-array systematic bias. M...

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Detalles Bibliográficos
Autores principales: Kang, Jia, Xu, Ethan Yixun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734108/
https://www.ncbi.nlm.nih.gov/pubmed/23885888
http://dx.doi.org/10.1186/1471-2164-14-507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734108/
https://www.ncbi.nlm.nih.gov/pubmed/23885888
http://dx.doi.org/10.1186/1471-2164-14-507

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