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AMD-Associated Genes Encoding Stress-Activated MAPK Pathway Constituents Are Identified by Interval-Based Enrichment Analysis

PURPOSE: To determine whether common DNA sequence variants within groups of genes encoding elements of stress-activated mitogen-activated protein kinase (MAPK) signaling pathways are, in aggregate, associated with advanced AMD (AAMD). METHODS: We used meta-regression and exact testing methods to ide...

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Detalles Bibliográficos
Autores principales: SanGiovanni, John Paul, Lee, Phil H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734129/
https://www.ncbi.nlm.nih.gov/pubmed/23940728
http://dx.doi.org/10.1371/journal.pone.0071239