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When ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling

Ubiquitination, the covalent attachment of ubiquitin to target proteins, has emerged as a ubiquitous post-translational modification (PTM) whose function extends far beyond its original role as a tag for protein degradation identified three decades ago. Although sharing parallel properties with phos...

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Detalles Bibliográficos
Autores principales: Nguyen, Lan K, Kolch, Walter, Kholodenko, Boris N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734146/
https://www.ncbi.nlm.nih.gov/pubmed/23902637
http://dx.doi.org/10.1186/1478-811X-11-52