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When ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling
Ubiquitination, the covalent attachment of ubiquitin to target proteins, has emerged as a ubiquitous post-translational modification (PTM) whose function extends far beyond its original role as a tag for protein degradation identified three decades ago. Although sharing parallel properties with phos...
Autores principales: | Nguyen, Lan K, Kolch, Walter, Kholodenko, Boris N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734146/ https://www.ncbi.nlm.nih.gov/pubmed/23902637 http://dx.doi.org/10.1186/1478-811X-11-52 |
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