Cargando…

Neuronal Apoptosis and Motor Deficits in Mice with Genetic Inhibition of GSK-3 Are Fas-Dependent

Glycogen synthase kinase-3 (GSK-3) inhibitors have been postulated as useful therapeutic tools for the treatment of chronic neurodegenerative and neuropsychiatric diseases. Nevertheless the clinical use of these inhibitors has been limited by their common side effects. Lithium, a non-selective GSK-3...

Descripción completa

Detalles Bibliográficos
Autores principales: Gómez-Sintes, Raquel, Lucas, José J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734180/
https://www.ncbi.nlm.nih.gov/pubmed/23940673
http://dx.doi.org/10.1371/journal.pone.0070952