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Low-dose monobutyl phthalate stimulates steroidogenesis through steroidogenic acute regulatory protein regulated by SF-1, GATA-4 and C/EBP-beta in mouse Leydig tumor cells

BACKGROUND: The ubiquitous use of dibutyl phthalate (DBP), one of the most widely used plasticizers, results in extensive exposure to humans and the environment. DBP and its major metabolite, monobutyl phthalate (MBP), may alter steroid biosynthesis and their exposure may lead to damage to male repr...

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Detalles Bibliográficos
Autores principales: Hu, Yanhui, Dong, Congcong, Chen, Minjian, Lu, Jing, Han, Xiumei, Qiu, Lianglin, Chen, Yansu, Qin, Jingjing, Li, Xiaocheng, Gu, Aihua, Xia, Yankai, Sun, Hong, Li, Zhong, Wang, Yubang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734203/
https://www.ncbi.nlm.nih.gov/pubmed/23889939
http://dx.doi.org/10.1186/1477-7827-11-72