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Role of PTPα in the Destruction of Periodontal Connective Tissues

IL-1β contributes to connective tissue destruction in part by up-regulating stromelysin-1 (MMP-3), which in fibroblasts is a focal adhesion-dependent process. Protein tyrosine phosphatase-α (PTPα) is enriched in and regulates the formation of focal adhesions, but the role of PTPα in connective tissu...

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Detalles Bibliográficos
Autores principales: Rajshankar, Dhaarmini, Sima, Corneliu, Wang, Qin, Goldberg, Stephanie R., Kazembe, Mwayi, Wang, Yongqiang, Glogauer, Michael, Downey, Gregory P., McCulloch, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734242/
https://www.ncbi.nlm.nih.gov/pubmed/23940616
http://dx.doi.org/10.1371/journal.pone.0070659