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Increased PRAME-Specific CTL Killing of Acute Myeloid Leukemia Cells by Either a Novel Histone Deacetylase Inhibitor Chidamide Alone or Combined Treatment with Decitabine

As one of the best known cancer testis antigens, PRAME is overexpressed exclusively in germ line tissues such as the testis as well as in a variety of solid and hematological malignant cells including acute myeloid leukemia. Therefore, PRAME has been recognized as a promising target for both active...

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Detalles Bibliográficos
Autores principales: Yao, Yushi, Zhou, Jihao, Wang, Lixin, Gao, Xiaoning, Ning, Qiaoyang, Jiang, Mengmeng, Wang, Jia, Wang, Lili, Yu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734248/
https://www.ncbi.nlm.nih.gov/pubmed/23940586
http://dx.doi.org/10.1371/journal.pone.0070522