A Novel Color Change Mechanism for Breast Cancer Biomarker Detection: Naphthoquinones as Specific Ligands of Human Arylamine N-Acetyltransferase 1

Human arylamine N-acetyltransferase 1 (hNAT1) has become an attractive potential biomarker for estrogen-receptor-positive breast cancers. We describe here the mechanism of action of a selective non-covalent colorimetric biosensor for the recognition of hNAT1 and its murine homologue, mNat2, over the...

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Detalles Bibliográficos
Autores principales: Laurieri, Nicola, Egleton, James E., Varney, Amy, Thinnes, Cyrille C., Quevedo, Camilo E., Seden, Peter T., Thompson, Sam, Rodrigues-Lima, Fernando, Dairou, Julien, Dupret, Jean-Marie, Russell, Angela J., Sim, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734253/
https://www.ncbi.nlm.nih.gov/pubmed/23940600
http://dx.doi.org/10.1371/journal.pone.0070600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734253/
https://www.ncbi.nlm.nih.gov/pubmed/23940600
http://dx.doi.org/10.1371/journal.pone.0070600

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