Regulators of Global Genome Repair Do Not Respond to DNA Damaging Therapy but Correlate with Survival in Melanoma

Nucleotide excision repair (NER) orchestrates the repair of helix distorting DNA damage, induced by both ultraviolet radiation (UVR) and cisplatin. There is evidence that the global genome repair (GGR) arm of NER is dysfunctional in melanoma and it is known to have limited induction in melanoma cell...

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Detalles Bibliográficos
Autores principales: Bowden, Nikola A., Ashton, Katie A., Vilain, Ricardo E., Avery-Kiejda, Kelly A., Davey, Ryan J., Murray, Heather C., Budden, Timothy, Braye, Stephen G., Zhang, Xu Dong, Hersey, Peter, Scott, Rodney J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734271/
https://www.ncbi.nlm.nih.gov/pubmed/23940574
http://dx.doi.org/10.1371/journal.pone.0070424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734271/
https://www.ncbi.nlm.nih.gov/pubmed/23940574
http://dx.doi.org/10.1371/journal.pone.0070424

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