Angiopoietin-2 Is Critical for Cytokine-Induced Vascular Leakage

Genetic experiments (loss-of-function and gain-of-function) have established the role of Angiopoietin/Tie ligand/receptor tyrosine kinase system as a regulator of vessel maturation and quiescence. Angiopoietin-2 (Ang-2) acts on Tie2-expressing resting endothelial cells as an antagonistic ligand to n...

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Detalles Bibliográficos
Autores principales: Benest, Andrew V., Kruse, Karoline, Savant, Soniya, Thomas, Markus, Laib, Anna M., Loos, Elias K., Fiedler, Ulrike, Augustin, Hellmut G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734283/
https://www.ncbi.nlm.nih.gov/pubmed/23940579
http://dx.doi.org/10.1371/journal.pone.0070459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734283/
https://www.ncbi.nlm.nih.gov/pubmed/23940579
http://dx.doi.org/10.1371/journal.pone.0070459

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