Cargando…

Angiopoietin-2 Is Critical for Cytokine-Induced Vascular Leakage

Genetic experiments (loss-of-function and gain-of-function) have established the role of Angiopoietin/Tie ligand/receptor tyrosine kinase system as a regulator of vessel maturation and quiescence. Angiopoietin-2 (Ang-2) acts on Tie2-expressing resting endothelial cells as an antagonistic ligand to n...

Descripción completa

Detalles Bibliográficos
Autores principales:	Benest, Andrew V., Kruse, Karoline, Savant, Soniya, Thomas, Markus, Laib, Anna M., Loos, Elias K., Fiedler, Ulrike, Augustin, Hellmut G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734283/ https://www.ncbi.nlm.nih.gov/pubmed/23940579 http://dx.doi.org/10.1371/journal.pone.0070459

Ejemplares similares

The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells
por: Savant, Soniya, et al.
Publicado: (2015)

Hypertension, Vascular Rarefaction and Angiopoietin-1
por: Bae, Jang-Whan
Publicado: (2011)

The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium
por: Anisimov, Andrey, et al.
Publicado: (2023)

Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2
por: Saharinen, Pipsa, et al.
Publicado: (2005)

Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions
por: Zheng, Wei, et al.
Publicado: (2014)

Enhanced notch signaling modulates unproductive revascularization in response to nitric oxide‐angiopoietin signaling in a mouse model of peripheral ischemia
por: Machado, Maria J. C., et al.
Publicado: (2019)

Role of Angiopoietin-2 in Vascular Physiology and Pathophysiology
por: Akwii, Racheal G., et al.
Publicado: (2019)

CSF Levels of Angiopoietin-2 Do Not Differ between Patients with CSF Fluid Leakage Syndrome and Controls
por: Pul, Refik, et al.
Publicado: (2015)

Pericyte-expressed Tie2 controls angiogenesis and vessel maturation
por: Teichert, Martin, et al.
Publicado: (2017)

Role of Angiopoietin-2 in Regulating Growth and Vascularity of Astrocytomas
por: Zadeh, Gelareh, et al.
Publicado: (2010)

Angiopoietin 2 Alters Pancreatic Vascularization in Diabetic Conditions
por: Calderari, Sophie, et al.
Publicado: (2012)

Prognostic role of plasma level of angiopoietin-1, angiopoietin-2, and vascular endothelial growth factor in hepatocellular carcinoma
por: Choi, Gwang Hyeon, et al.
Publicado: (2021)

Circulating angiopoietin-1 and angiopoietin-2 in critically ill patients: development and clinical application of two new immunoassays
por: Lukasz, Alexander, et al.
Publicado: (2008)

Angiopoietin-2: Modulator of Vascular Permeability in Acute Lung Injury?
por: Hashimoto, Tomoki, et al.
Publicado: (2006)

Vascular endothelial growth factors and angiopoietins as new players in mastocytosis
por: Marcella, Simone, et al.
Publicado: (2021)

Involvement of Angiopoietin 2 and vascular endothelial growth factor in uveitis
por: Suzuki, Kayo, et al.
Publicado: (2023)

Anti-angiogenic Targets: Angiopoietin and Angiopoietin Receptors
por: Kiss, Elina A., et al.
Publicado: (2019)

Targeting vascular leakage in lung inflammation
por: Li, Liang, et al.
Publicado: (2015)

Kinetics of Plasma Cytokines, Angiopoietin-2, and C-Reactive Protein in Dogs With Gastric Dilatation Volvulus
por: Brunner, Anna, et al.
Publicado: (2021)

Association of serum angiopoietin-1, angiopoietin-2 and angiopoietin-2 to angiopoietin-1 ratio with heart failure in patients with acute myocardial infarction
por: CHEN, SHAOMIN, et al.
Publicado: (2013)

Vascular Leakage in Dengue Hemorrhagic Fever Is Associated with Dengue Infected Monocytes, Monocyte Activation/Exhaustion, and Cytokines Production
por: Chunhakan, Sirichan, et al.
Publicado: (2015)

The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner
por: Luck, Robert, et al.
Publicado: (2021)

Cooperation of Angiopoietin-2 and Angiopoietin-4 in Schlemm's Canal Maintenance
por: Kapiainen, Emmi, et al.
Publicado: (2022)

Acute Systemic Infection with Dengue Virus Leads to Vascular Leakage and Death through Tumor Necrosis Factor-α and Tie2/Angiopoietin Signaling in Mice Lacking Type I and II Interferon Receptors
por: Phanthanawiboon, Supranee, et al.
Publicado: (2016)

Angiopoietin-Like 7 Is an Anti-Angiogenic Protein Required to Prevent Vascularization of the Cornea
por: Toyono, Tetsuya, et al.
Publicado: (2015)

Angiopoietin-2 regulated by progesterone induces uterine vascular remodeling during pregnancy
por: Park, Yang-Gyu, et al.
Publicado: (2020)

Pericyte Insulin Receptors Modulate Retinal Vascular Remodeling and Endothelial Angiopoietin Signaling
por: Warmke, Nele, et al.
Publicado: (2021)

Aflibercept Suppression of Angiopoietin-2 in a Rabbit Retinal Vascular Hyperpermeability Model
por: Lange, Claudia, et al.
Publicado: (2023)

Aflibercept Suppression of Angiopoietin-2 in a Rabbit Retinal Vascular Hyperpermeability Model
por: Lange, Claudia, et al.
Publicado: (2023)

Angiopoietin-2 and Angiopoietin-2/Angiopoietin-1 Ratio as Indicators of Potential Severity of Plasmodium vivax Malaria in Patients with Thrombocytopenia
por: Gomes, Luciano Teixeira, et al.
Publicado: (2014)

Prognostic significance of the angiopoietin-2/angiopoietin-1 and angiopoietin-1/Tie-2 ratios for early sepsis in an emergency department
por: Fang, Yingying, et al.
Publicado: (2015)

A Critical Role for Perivascular Cells in Amplifying Vascular Leakage Induced by Dengue Virus Nonstructural Protein 1
por: Cheung, Yin P., et al.
Publicado: (2020)

Correction: Angiopoietin-2 and Angiopoietin-2/Angiopoietin-1 Ratio as Indicators of Potential Severity of Plasmodium vivax Malaria in Patients with Thrombocytopenia
Publicado: (2015)

Bench-to-bedside review: Angiopoietin signalling in critical illness – a future target?
por: van Meurs, Matijs, et al.
Publicado: (2009)

Akt1-dependent expression of angiopoietin 1 and 2 in vascular smooth muscle cells leads to vascular stabilization
por: Ha, Jung Min, et al.
Publicado: (2022)

Angiopoietins and diabetic nephropathy
por: Gnudi, Luigi
Publicado: (2016)

Angiopoietin-1, Angiopoietin-2 and Bicarbonate as Diagnostic Biomarkers in Children with Severe Sepsis
por: Wang, Kun, et al.
Publicado: (2014)

Angiopoietin-2, Angiopoietin-1 and subclinical cardiovascular disease in Chronic Kidney Disease
por: Tsai, Yi-Chun, et al.
Publicado: (2016)

Angiopoietin-like 3 inhibition of endothelial lipase is not modulated by angiopoietin-like 8
por: Sylvers-Davie, Kelli L., et al.
Publicado: (2021)

Excess Circulating Angiopoietin-2 May Contribute to Pulmonary Vascular Leak in Sepsis in Humans
por: Parikh, Samir M, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_g4o9283rmm1cjtpup2jg04vo00