P2X7 Receptor Activation Impairs Exogenous MHC Class I Oligopeptides Presentation in Antigen Presenting Cells

Major histocompatibility complex class I (MHC I) on antigen presenting cells (APCs) is a potent molecule to activate CD8(+) T cells and initiate immunity. P2X7 receptors (P2X7Rs) are present on the plasma membrane of APCs to sense the extracellular danger signal adenosine-5′-triphosphate (ATP). P2X7...

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Detalles Bibliográficos
Autores principales: Baroja-Mazo, Alberto, Barberà-Cremades, Maria, Pelegrín, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734297/
https://www.ncbi.nlm.nih.gov/pubmed/23940597
http://dx.doi.org/10.1371/journal.pone.0070577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734297/
https://www.ncbi.nlm.nih.gov/pubmed/23940597
http://dx.doi.org/10.1371/journal.pone.0070577

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