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A Cellular Pathway Involved in Clara Cell to Alveolar Type II Cell Differentiation after Severe Lung Injury

Regeneration of alveolar epithelia following severe pulmonary damage is critical for lung function. We and others have previously shown that Scgb1a1-expressing cells, most likely Clara cells, can give rise to newly generated alveolar type 2 cells (AT2s) in response to severe lung damage induced by e...

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Detalles Bibliográficos
Autores principales: Zheng, Dahai, Limmon, Gino V., Yin, Lu, Leung, Nicola H. N., Yu, Hanry, Chow, Vincent T. K., Chen, Jianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734298/
https://www.ncbi.nlm.nih.gov/pubmed/23940685
http://dx.doi.org/10.1371/journal.pone.0071028