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Increased Cellular Senescence and Vascular Rarefaction Exacerbate the Progression of Kidney Fibrosis in Aged Mice Following Transient Ischemic Injury

Recent findings indicate that elderly patients with acute kidney injury (AKI) have an increased incidence of progression to chronic kidney disease (CKD) due to incomplete recovery from an acute insult. In the current study, a co-morbid model of AKI was developed to better mimic the patient populatio...

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Detalles Bibliográficos
Autores principales: Clements, Meghan E., Chaber, Christopher J., Ledbetter, Steven R., Zuk, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734312/
https://www.ncbi.nlm.nih.gov/pubmed/23940580
http://dx.doi.org/10.1371/journal.pone.0070464