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Increased Cellular Senescence and Vascular Rarefaction Exacerbate the Progression of Kidney Fibrosis in Aged Mice Following Transient Ischemic Injury
Recent findings indicate that elderly patients with acute kidney injury (AKI) have an increased incidence of progression to chronic kidney disease (CKD) due to incomplete recovery from an acute insult. In the current study, a co-morbid model of AKI was developed to better mimic the patient populatio...
Autores principales: | Clements, Meghan E., Chaber, Christopher J., Ledbetter, Steven R., Zuk, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734312/ https://www.ncbi.nlm.nih.gov/pubmed/23940580 http://dx.doi.org/10.1371/journal.pone.0070464 |
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