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Triptolide, an active compound identified in a traditional Chinese herb, induces apoptosis of rheumatoid synovial fibroblasts

BACKGROUND: Extracts of Tripterygium wilfordii Hook F (TWHF), a traditional Chinese herb, have been reported to show efficacy in patients with rheumatoid arthritis (RA). Since RA is not only characterized by inflammation but also by synovial proliferation in the joints, we examined whether triptolid...

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Detalles Bibliográficos
Autores principales: Kusunoki, Natsuko, Yamazaki, Ryuta, Kitasato, Hidero, Beppu, Moroe, Aoki, Haruhito, Kawai, Shinichi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC373449/
https://www.ncbi.nlm.nih.gov/pubmed/15040811
http://dx.doi.org/10.1186/1471-2210-4-2