Recruitment of Normal Stem Cells to an Oncogenic Phenotype by Noncontiguous Carcinogen-Transformed Epithelia Depends on the Transforming Carcinogen

Background: Cancer stem cells (CSCs) drive tumor initiation, progression, and metastasis. The microenvironment is critical to the fate of CSCs. We have found that a normal stem cell (NSC) line from human prostate (WPE-stem) is recruited into CSC-like cells by nearby, but noncontiguous, arsenic-trans...

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Detalles Bibliográficos
Autores principales: Xu, Yuanyuan, Tokar, Erik J., Person, Rachel J., Orihuela, Ruben G., Ngalame, Ntube N.O., Waalkes, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734505/
https://www.ncbi.nlm.nih.gov/pubmed/23687063
http://dx.doi.org/10.1289/ehp.1306714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734505/
https://www.ncbi.nlm.nih.gov/pubmed/23687063
http://dx.doi.org/10.1289/ehp.1306714

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