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A novel technique for quantifying changes in vascular density, endothelial cell proliferation and protein expression in response to modulators of angiogenesis using the chick chorioallantoic membrane (CAM) assay

Reliable quantitative evaluation of molecular pathways is critical for both drug discovery and treatment monitoring. We have modified the CAM assay to quantitatively measure vascular density, endothelial proliferation, and changes in protein expression in response to anti-angiogenic and pro-angiogen...

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Detalles Bibliográficos
Autores principales: Miller, Walter J, Kayton, Mark L, Patton, Angela, O'Connor, Sarah, He, Mei, Vu, Huan, Baibakov, Galina, Lorang, Dominique, Knezevic, Vladimir, Kohn, Elise, Alexander, H Richard, Stirling, David, Payvandi, Faribourz, Muller, George W, Libutti, Steven K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC373457/
https://www.ncbi.nlm.nih.gov/pubmed/14754458
http://dx.doi.org/10.1186/1479-5876-2-4