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Viral Delivery of Antioxidant Genes as a Therapeutic Strategy in Experimental Models of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder with no effective treatment to date. Despite its multi-factorial aetiology, oxidative stress is hypothesized to be one of the key pathogenic mechanisms. It is thus proposed that manipulation of the expression of antioxid...

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Detalles Bibliográficos
Autores principales: Nanou, Aikaterini, Higginbottom, Adrian, Valori, Chiara F, Wyles, Matthew, Ning, Ke, Shaw, Pamela, Azzouz, Mimoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734656/
https://www.ncbi.nlm.nih.gov/pubmed/23732987
http://dx.doi.org/10.1038/mt.2013.115