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TGF-β1 and hypoxia-dependent expression of MKP-1 leads tumor resistance to death receptor-mediated cell death

Sporadic occurrence of transformed tumor cells is under the surveillance of the host immune system and such cells are effectively eliminated by immune-mediated cell death. During tumor progression, the antitumor effects of the tumor microenvironment are suppressed by diverse immunosuppressive mechan...

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Detalles Bibliográficos
Autores principales: Park, J, Lee, J, Kang, W, Chang, S, Shin, E-C, Choi, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734814/
https://www.ncbi.nlm.nih.gov/pubmed/23449457
http://dx.doi.org/10.1038/cddis.2013.42