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Myostatin induces mitochondrial metabolic alteration and typical apoptosis in cancer cells

Myostatin, a member of the transforming growth factor-β superfamily, regulates the glucose metabolism of muscle cells, while dysregulated myostatin activity is associated with a number of metabolic disorders, including muscle cachexia, obesity and type II diabetes. We observed that myostatin induced...

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Detalles Bibliográficos
Autores principales: Liu, Y, Cheng, H, Zhou, Y, Zhu, Y, Bian, R, Chen, Y, Li, C, Ma, Q, Zheng, Q, Zhang, Y, Jin, H, Wang, X, Chen, Q, Zhu, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734823/
https://www.ncbi.nlm.nih.gov/pubmed/23412387
http://dx.doi.org/10.1038/cddis.2013.31