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Role of protein kinase C δ in ER stress and apoptosis induced by oxidized LDL in human vascular smooth muscle cells

During atherogenesis, excess amounts of low-density lipoproteins (LDL) accumulate in the subendothelial space where they undergo oxidative modifications. Oxidized LDL (oxLDL) alter the fragile balance between survival and death of vascular smooth muscle cells (VSMC) thereby leading to plaque instabi...

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Detalles Bibliográficos
Autores principales: Larroque-Cardoso, P, Swiader, A, Ingueneau, C, Nègre-Salvayre, A, Elbaz, M, Reyland, M E, Salvayre, R, Vindis, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734829/
https://www.ncbi.nlm.nih.gov/pubmed/23449456
http://dx.doi.org/10.1038/cddis.2013.47