MiR203 mediates subversion of stem cell properties during mammary epithelial differentiation via repression of ΔNP63α and promotes mesenchymal-to-epithelial transition

During reproductive life, the mammary epithelium undergoes consecutive cycles of proliferation, differentiation and apoptosis. Doing so relies on the retained proliferative capacity, prolonged lifespan and developmental potency of mammary stem cells (MaSCs). ΔNp63α, the predominant TP63 isoform in m...

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Detalles Bibliográficos
Autores principales: DeCastro, A J, Dunphy, K A, Hutchinson, J, Balboni, A L, Cherukuri, P, Jerry, D J, DiRenzo, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734833/
https://www.ncbi.nlm.nih.gov/pubmed/23449450
http://dx.doi.org/10.1038/cddis.2013.37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734833/
https://www.ncbi.nlm.nih.gov/pubmed/23449450
http://dx.doi.org/10.1038/cddis.2013.37

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