PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells

Mounting evidence shows that selenium possesses chemotherapeutic potential against tumor cells, including leukemia, prostate cancer and colorectal cancer (CRC) cells. However, the detailed mechanism by which sodium selenite specifically kills tumor cells remains unclear. Herein, we demonstrated that...

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Detalles Bibliográficos
Autores principales: Luo, H, Yang, Y, Duan, J, Wu, P, Jiang, Q, Xu, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734838/
https://www.ncbi.nlm.nih.gov/pubmed/23392169
http://dx.doi.org/10.1038/cddis.2013.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734838/
https://www.ncbi.nlm.nih.gov/pubmed/23392169
http://dx.doi.org/10.1038/cddis.2013.3

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