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Conformational altered p53 affects neuronal function: relevance for the response to toxic insult and growth-associated protein 43 expression

The role of p53 in neurodegenerative diseases is essentially associated with neuronal death. Recently an alternative point of view is emerging, as altered p53 conformation and impaired protein function have been found in fibroblasts and blood cells derived from Alzheimer's disease patients. Her...

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Detalles Bibliográficos
Autores principales: Buizza, L, Prandelli, C, Bonini, S A, Delbarba, A, Cenini, G, Lanni, C, Buoso, E, Racchi, M, Govoni, S, Memo, M, Uberti, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734841/
https://www.ncbi.nlm.nih.gov/pubmed/23392172
http://dx.doi.org/10.1038/cddis.2013.13