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Conformational altered p53 affects neuronal function: relevance for the response to toxic insult and growth-associated protein 43 expression
The role of p53 in neurodegenerative diseases is essentially associated with neuronal death. Recently an alternative point of view is emerging, as altered p53 conformation and impaired protein function have been found in fibroblasts and blood cells derived from Alzheimer's disease patients. Her...
Autores principales: | Buizza, L, Prandelli, C, Bonini, S A, Delbarba, A, Cenini, G, Lanni, C, Buoso, E, Racchi, M, Govoni, S, Memo, M, Uberti, D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734841/ https://www.ncbi.nlm.nih.gov/pubmed/23392172 http://dx.doi.org/10.1038/cddis.2013.13 |
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