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Paradoxical role of autophagy in the dysplastic and tumor-forming stages of hepatocarcinoma development in rats

Many reports have shown that autophagy has a role as both a promoter and inhibitor in tumor development. However, the mechanism of this paradox is unknown. Tumor development is a multistep process. Therefore, we investigated whether the role of autophagy in hepatocarcinoma formation depended on the...

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Detalles Bibliográficos
Autores principales: Sun, K, Guo, X-l, Zhao, Q-d, jing, Y-y, Kou, X-r, Xie, X-q, Zhou, Y, Cai, N, Gao, L, Zhao, X, Zhang, S-s, Song, J-r, Li, D, Deng, W-j, Li, R, Wu, M-c, Wei, L-x
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734842/
https://www.ncbi.nlm.nih.gov/pubmed/23429287
http://dx.doi.org/10.1038/cddis.2013.35