Cargando…

Paradoxical role of autophagy in the dysplastic and tumor-forming stages of hepatocarcinoma development in rats

Many reports have shown that autophagy has a role as both a promoter and inhibitor in tumor development. However, the mechanism of this paradox is unknown. Tumor development is a multistep process. Therefore, we investigated whether the role of autophagy in hepatocarcinoma formation depended on the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, K, Guo, X-l, Zhao, Q-d, jing, Y-y, Kou, X-r, Xie, X-q, Zhou, Y, Cai, N, Gao, L, Zhao, X, Zhang, S-s, Song, J-r, Li, D, Deng, W-j, Li, R, Wu, M-c, Wei, L-x
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734842/ https://www.ncbi.nlm.nih.gov/pubmed/23429287 http://dx.doi.org/10.1038/cddis.2013.35

Ejemplares similares

Piperlongumine induces autophagy by targeting p38 signaling
por: Wang, Y, et al.
Publicado: (2013)

β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy
por: Liu, J, et al.
Publicado: (2016)

Resveratrol and STAT inhibitor enhance autophagy in ovarian cancer cells
por: Zhong, L-X, et al.
Publicado: (2016)

DLC-1 is an independent prognostic marker and potential therapeutic target in hepatocellular cancer
por: Song, L. J., et al.
Publicado: (2016)

Association of improved overall survival with decreased distant metastasis following asparaginase-based chemotherapy and radiotherapy for intermediate- and high-risk early-stage extranodal nasal-type NK/T-cell lymphoma: a CLCG study
por: Zheng, X., et al.
Publicado: (2021)

Factors associated with Staphylococcus aureus nasal carriage and molecular characteristics among the general population at a Medical College Campus in Guangzhou, South China
por: Chen, B. J., et al.
Publicado: (2017)

S234: CLINICAL-GRADE MBIL21/4-1BBL EXPANDED NK CELLS EXHIBIT STRONGER COMPETENCE COMPARED WITH PRIMARY NK CELLS AGAINST HCMV INFECTION
por: Shang, Q.-N., et al.
Publicado: (2022)

Uncoupling DAPK1 from NMDA receptor GluN2B subunit exerts rapid antidepressant-like effects
por: Li, S-X, et al.
Publicado: (2018)

Inhibition of ATG12-mediated autophagy by miR-214 enhances radiosensitivity in colorectal cancer
por: Hu, J. L., et al.
Publicado: (2018)

Anti-angiogenesis therapy based on the bone marrow-derived stromal cells genetically engineered to express sFlt-1 in mouse tumor model
por: Hu, M, et al.
Publicado: (2008)

Akt inhibition attenuates rasfonin-induced autophagy and apoptosis through the glycolytic pathway in renal cancer cells
por: Lu, Q, et al.
Publicado: (2015)

P1654: COMPLEMENT ACTIVATION REGULATES PLATELET HOMEOSTASIS BY ARRESTING THE ANTI-INFLAMMATORY EFFECTS OF INTERLEUKIN-35 IN IMMUNE THROMBOCYTOPENIA
por: Gui, R.-Y., et al.
Publicado: (2022)

Fusing atomic W states via quantum Zeno dynamics
por: Ji, Y. Q., et al.
Publicado: (2017)

Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: implications for age-related macular degeneration
por: Zhang, J, et al.
Publicado: (2015)

Osteocalcin prevents insulin resistance, hepatic inflammation, and activates autophagy associated with high-fat diet–induced fatty liver hemorrhagic syndrome in aged laying hens
por: Wu, X.L., et al.
Publicado: (2020)

Autophagy-dependent generation of Axin2+ cancer stem-like cells promotes hepatocarcinogenesis in liver cirrhosis
por: Li, J, et al.
Publicado: (2017)

Association between MFN2 gene polymorphisms and the risk and prognosis of acute liver failure: a case-control study in a Chinese population
por: Wei, Y.-L., et al.
Publicado: (2017)

Effects of parental dietary linoleic acid on growth performance, antioxidant capacity, and lipid metabolism in domestic pigeons (Columba livia)
por: Xu, Q.Q., et al.
Publicado: (2020)

Novel genetic environment of the plasmid-mediated KPC-3 gene detected in Escherichia coli and Citrobacter freundii isolates from China
por: Li, G., et al.
Publicado: (2010)

Autophagy prevents irradiation injury and maintains stemness through decreasing ROS generation in mesenchymal stem cells
por: Hou, J, et al.
Publicado: (2013)

Edaravone protects endotoxin-induced liver injury by inhibiting apoptosis and reducing proinflammatory cytokines
por: Zong, L., et al.
Publicado: (2014)

Effects of early post-hatch feeding on the growth performance, hormone secretion, intestinal morphology, and intestinal microbiota structure in broilers
por: Li, D.L., et al.
Publicado: (2022)

Yeast CUP1 protects HeLa cells against copper-induced stress
por: Xie, X.X., et al.
Publicado: (2015)

P01.04. Attenuation of neurological dysfunction and brain infarction with a chinese herbal formula in ischemia-reperfusion induced brain injury of mice
por: Cheng, F, et al.
Publicado: (2012)

Effect of Different Inclusion Level of Condensed Distillers Solubles Ratios and Oil Content on Amino Acid Digestibility of Corn Distillers Dried Grains with Solubles in Growing Pigs
por: Li, P., et al.
Publicado: (2015)

The effectiveness of eHealth interventions on moderate-to-vigorous intensity physical activity among cardiac rehabilitation participants: a systematic review and meta-analysis
por: Yu, T Z, et al.
Publicado: (2022)

Comprehensive analysis of the PD-L1 and immune infiltrates of N6-methyladenosine related long non-coding RNAs in bladder cancer
por: Xue, M. Q., et al.
Publicado: (2022)

Involvement of Src tyrosine kinase and protein kinase C in the expression of macrophage migration inhibitory factor induced by H(2)O(2) in HL-1 mouse cardiac muscle cells
por: Rao, F., et al.
Publicado: (2013)

Etiology, comorbidity and prognosis of hospitalized patients with congestive heart failure
por: Zhao, Y, et al.
Publicado: (2010)

Possible itinerant excitations and quantum spin state transitions in the effective spin-1/2 triangular-lattice antiferromagnet Na(2)BaCo(PO(4))(2)
por: Li, N., et al.
Publicado: (2020)

Ras-association domain family 10 acts as a novel tumor suppressor through modulating MMP2 in hepatocarcinoma
por: Liu, W, et al.
Publicado: (2016)

Effect of Bacillus subtilis on corrosion behavior of 10MnNiCrCu steel in marine environment
por: Wang, Y. S., et al.
Publicado: (2020)

Effects of early weaning on intestinal morphology, digestive enzyme activity, antioxidant status, and cytokine status in domestic pigeon squabs (Columba livia)
por: Wen, J.S., et al.
Publicado: (2021)

Risk factors for death from hand–foot–mouth disease: a meta-analysis
por: Ni, X.F., et al.
Publicado: (2020)

Effects of first feed intake time on growth performance, nutrient apparent metabolic rate and intestinal digestive enzyme activities in broilers
por: Wang, J. S., et al.
Publicado: (2018)

Effects of dietary incorporation of linseed oil with soybean isoflavone on fatty acid profiles and lipid metabolism-related gene expression in breast muscle of chickens
por: Gou, Z. Y., et al.
Publicado: (2020)

Large adipocytes function as antigen-presenting cells to activate CD4(+) T cells via upregulating MHCII in obesity
por: Xiao, L, et al.
Publicado: (2016)

Association between the c.910A>G genetic variant of the XRCC1 gene and susceptibility to esophageal cancer in the Chinese Han population
por: Chen, X.Q., et al.
Publicado: (2013)

BRCC2 inhibits breast cancer cell growth and metastasis in vitro and in vivo via downregulating AKT pathway
por: Li, X, et al.
Publicado: (2013)

Tunable electronic properties and related functional devices for ferroelectric In(2)Se(3)/MoSSe van der Waals heterostructures
por: Zhang, Y., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tf42g2rtd7i7qf852sdfcdr374