IgG Protease Mac/IdeS Is Not Essential for Phagocyte Resistance or Mouse Virulence of M1T1 Group A Streptococcus

The Mac/IdeS protein of group A Streptococcus (GAS) is a secreted cysteine protease with cleavage specificity for IgG and is highly expressed in the GAS serotype M1T1 clone, which is the serotype most frequently isolated from patients with life-threatening invasive infections. While studies of Mac/I...

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Detalles Bibliográficos
Autores principales: Okumura, Cheryl Y. M., Anderson, Ericka L., Döhrmann, Simon, Tran, Dan N., Olson, Joshua, von Pawel-Rammingen, Ulrich, Nizet, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735186/
https://www.ncbi.nlm.nih.gov/pubmed/23900173
http://dx.doi.org/10.1128/mBio.00499-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735186/
https://www.ncbi.nlm.nih.gov/pubmed/23900173
http://dx.doi.org/10.1128/mBio.00499-13

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