Daptomycin-Resistant Enterococcus faecalis Diverts the Antibiotic Molecule from the Division Septum and Remodels Cell Membrane Phospholipids

Treatment of multidrug-resistant enterococci has become a challenging clinical problem in hospitals around the world due to the lack of reliable therapeutic options. Daptomycin (DAP), a cell membrane-targeting cationic antimicrobial lipopeptide, is the only antibiotic with in vitro bactericidal acti...

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Detalles Bibliográficos
Autores principales: Tran, Truc T., Panesso, Diana, Mishra, Nagendra N., Mileykovskaya, Eugenia, Guan, Ziqianq, Munita, Jose M., Reyes, Jinnethe, Diaz, Lorena, Weinstock, George M., Murray, Barbara E., Shamoo, Yousif, Dowhan, William, Bayer, Arnold S., Arias, Cesar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735187/
https://www.ncbi.nlm.nih.gov/pubmed/23882013
http://dx.doi.org/10.1128/mBio.00281-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735187/
https://www.ncbi.nlm.nih.gov/pubmed/23882013
http://dx.doi.org/10.1128/mBio.00281-13

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