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Metastasis of aggressive amoeboid sarcoma cells is dependent on Rho/ROCK/MLC signaling

BACKGROUND: Although there is extensive evidence for the amoeboid invasiveness of cancer cells in vitro, much less is known about the role of amoeboid invasiveness in metastasis and the importance of Rho/ROCK/MLC signaling in this process. RESULTS: We analyzed the dependence of amoeboid invasiveness...

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Detalles Bibliográficos
Autores principales: Kosla, Jan, Paňková, Daniela, Plachý, Jiří, Tolde, Ondřej, Bicanová, Kristýna, Dvořák, Michal, Rösel, Daniel, Brábek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735423/
https://www.ncbi.nlm.nih.gov/pubmed/23899007
http://dx.doi.org/10.1186/1478-811X-11-51